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Lorenzen, Inken Kiel

Expertise: Molecular mechanism of protein regulation and signal transduction, cytokine/ cytokine-receptor, metalloproteases, shedding as irreversible regulatory switch/ posttranslational modification; disulfide-isomerisation as a regulatory mechanism; protein structure-function analysis; recombinant protein expression, purification and characterisation; protein-protein interaction; site directed mutagenesis, cell-biology

Methodology provided: Flow cytometry analysis; analysis of protein-protein interaction by methods like NMR and co-immunoprecipitation; recombinant protein expression using pro- as well as eukaryotic expression systems; protein purification and characterisation by FPLC, HPLC, CD-spectroscopy, DLS, NMR; cell culture and functional studies of cytokines, cytokine-receptors and membrane-bound metalloproteases